A Mathematical Reliability Growth Model using for Acute HPA Axis Responses, Heart Rate and Mood Changes to Psychosocial Stress in Human at Different Times of Day
نویسندگان
چکیده
There is evidence showing that HPA axis responses to pharmacological provocation depend on time of day with larger cortisol responses in the afternoon and evening compared to the morning hours. However, it is still unknown whether HPA axis responses to psychological stress are affected by time of day and whether they can be assessed with equal reliability in the morning and afternoon, respectively.Software Reliability Model is categorized into two, one is static model and the other one is dynamic model. Dynamic models observe the temporary behavior of debugging process during testing phase. In Static Models, modeling and analysis of program logic is done on the same code. A Model which describes about error detection in software Reliability is called Software Reliability Growth Model. This paper reviews various existing software reliability models and there failure intensity function and the mean value function. On the basis of this review a model is proposed for the software reliability having different mean value function and failure intensity function. Finally we conclude our Mathematical results in the (4.1.figure) are well fitted with the Reliability Growth model and the maximum value of ACTH, Salivary cortisol, Total plasma cortisol, at the time has been obtained. This will be helpful for the medical professional.
منابع مشابه
Hypothalamus Pituitary Adrenal axis and stimulatory G proteins signaling role in nociceptive changes induced by forced swim stress
Introduction: Different mechanisms are involved in stress induced analgesia (SIA) and hyperalgesia (SIH). Repeated stress induces development of tolerance to SIA. The role of HPA axis and Gs signaling pathway in these effects are investigated in the current study. Methods: Forced swim stress (5 min/day) in water (20±1 ºC) was employed to adult male Wistar rats (200-250 g). The nociceptive t...
متن کاملEvidence for a normal HPA axis response to psychosocial stress in patients remitted from depression.
The purpose of this study was to investigate subjective mood and the effect of a psychosocial stress challenge on cortisol response in patients remitted from depression in comparison to healthy controls. Only few studies on small samples have been conducted on the influence of psychosocial stress on HPA system responsivity in this group. Results regarding patients who have achieved clinical rem...
متن کاملAttenuation of the hypothalamic-pituitary-adrenal axis responsivity to the Trier Social Stress Test by the benzodiazepine alprazolam.
Little is known about effects of commonly used anxiolytic drugs on psychologically evoked responses of two major stress systems, the hypothalamic-pituitary-adrenal (HPA) and the sympathetic-adrenal-medullary (SAM) axis. The purpose of the present study was to assess effects of the anxiolytic alprazolam on responses of the HPA and the SAM axes to a standardized psychosocial stress protocol, the ...
متن کاملThe BDNF Val66Met polymorphism affects HPA-axis reactivity to acute stress.
BACKGROUND Growing evidence suggests that individual differences in HPA-axis reactivity to psychosocial stress are partly due to heritable influences. However, knowledge about the role of specific genetic variants remains very limited to date. Since brain-derived neurotrophic factor (BDNF) not only exhibits neurotrophic actions but is also involved in the regulation of hypothalamic neuropeptide...
متن کاملInvestigation of the relation between the hypothalamus-pituitary-adrenal (HPA) axis activity, IL-6 and hyperalgesia during chronic inflammation due to rheumatoid arthritis (RA) in male rats.
Introduction: The activity of Hypothalamus-Pituitary-Adrenal (HPA) axis is increased following inflammation due to its closed relation with immune system. This axis indicates an increased secretion of ACTH, and corticosterone during acute inflammation while little is known about its activity during chronic inflammation such as rheumatoid arthritis (RA). In this study we measured the products...
متن کامل